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  4. Hydrophobic ceramic capillary membranes for versatile virus filtration
 
Zitierlink DOI
10.26092/elib/2493
Verlagslink DOI
10.1016/j.memsci.2018.10.022

Hydrophobic ceramic capillary membranes for versatile virus filtration

Veröffentlichungsdatum
2018-10-23
Autoren
Bartels, Julia  
Batista, Artur Guedert  
Kroll, Stephen  
Maas, Michael  
Rezwan, Kurosch  
Zusammenfassung
In this study, we present hydrophobic yttria-stabilized zirconia capillary membranes conditioned for virus filtration. These macroporous ceramic filters (d50 = 150 nm) efficiently extract viruses regardJess of their surface charge with high throughput rates. For hydrophobic functionalization of the ceramic membranes we used two different silanes, n-hexyltriethoxysilane (HTS, C6-chain) and n-octyltriethoxysilane (OTS, C8-chain), in three different molarities. The virus retention of the membranes is tested in dead-end mode by intracapillary virus feeding using two small bacteriophages as model species: MS2 and PhiX174. Virus retention increases most strongly for hydrophobic capillaries functionalized with 0.05 M OTS, showing a virtually complete retention with log-reduction values (LRVs) of - 9 for both bacteriophages compared to the non-functionalized membrane with LRVs of 0.3 ± 0.1 for MS2 and 3.4 ± 0.2 for PhiXl 74. The functionalized membranes allow a high membrane flux of - 150 L/(m2hbar), with throughput rates up to - 400 L/(m2 h) while maintaining high filtration efficiency. Even under varying feed conditions using only mono- or divalent salt ions or pH values ranging from 3 to 9, retention capacities of the capillary membranes are high. Accordingly, such
hydrophobic ceramic membranes offer a versatile alternative to conventional polymeric membranes for virus removal with greatly improved membrane flux.
Schlagwörter
Mimenima
Verlag
Elsevier
Institution
Universität Bremen  
Fachbereich
Fachbereich 04: Produktionstechnik, Maschinenbau & Verfahrenstechnik (FB 04)  
Institute
MAPEX Center for Materials and Processes  
Dokumenttyp
Artikel/Aufsatz
Zeitschrift/Sammelwerk
Journal of Membrane Science  
Band
570-571
Startseite
85
Endseite
92
Seitenzahl
8
Zweitveröffentlichung
Ja
Dokumentversion
Postprint
Lizenz
https://creativecommons.org/licenses/by-nc-nd/4.0/
Sprache
Englisch
Dateien
Lade...
Vorschaubild
Name

J. Bartels, A.G. Batista, S. Kroll, M. Maas, K. Rezwan, Hydrophobic ceramic capillary membranes for versatile virus filtration_2019_accepted version.pdf

Size

1.5 MB

Format

Adobe PDF

Checksum

(MD5):4b128231c33fa35f756b0500026f2095

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