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Citation link: https://doi.org/10.26092/elib/2459

Publisher DOI: https://doi.org/10.1016/j.ces.2016.07.020
Y. Wang, F. Du, G.R. Pesch, J. Köser, M. Baune, J.Thöming, Microparticle trajectories in a high-throughput channel_2016_accepted version_Deckblatt_pdfa1.pdf
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Microparticle trajectories in a high-throughput channel for contact-free fractionation by dielectrophoresis


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Y. Wang, F. Du, G.R. Pesch, J. Köser, M. Baune, J.Thöming, Microparticle trajectories in a high-throughput channel_2016_accepted version_Deckblatt_pdfa1.pdf1.4 MBAdobe PDFView/Open
Authors: Wang, Yan 
Du, Fei 
Pesch, Georg R.  
Köser, Jan 
Baune, Michael 
Thöming, Jorg  
Abstract: 
Continuous, contact-free fractionation of sensitive microparticles at high throughput is a challenge. For this purpose, we developed a sheath flow assisted dielectrophoretic (DEP) field-flow separator with a tailored arrangement of cylindrical interdigitated electrodes (cIDE) and observed size-dependent trajectories of dispersed particles. Using a voltage input of 200 Veff at a frequency of 200 kHz, polystyrene particles (45, 25, and 11 µm in diameter) levitated to different heights along the channel length due to a negative DEP force. Experimental observations agree well with simulated particle trajectories that were obtained by a modified Lagrangian particle tracking model in combination with Laplace's and Navier–Stokes equations. By exploiting the size-dependent levitation height difference the desired particle size fraction can be collected at a specific channel length. The required channel length of the proposed cIDE separator increases with decreasing particle size to be separated. The quality of theoretical fractionation, which we quantify by resolution, improves strongly with reduced collector width, reduced volume flow rate and increased voltage input. The sensitivity of these dependencies increases with decreasing particle size. We calculated a theoretical throughput of up to 47 mL min−1 when trading-off design and operation parameters, allowing for contact-free fractionation of sensitive microparticles with negligible shear stress.
Keywords: Fractionation; Dielectrophoresis; Particle trajectory; Resolution; High throughput; Mimenima
Issue Date: 22-Jul-2016
Publisher: Elsevier
Project: MIMENIMA GRK 1860 
Funders: Deutsche Forschungsgemeinschaft
Grant number: 601090
Journal/Edited collection: Chemical Engineering Science 
Start page: 34
End page: 44
Band: 153
Type: Artikel/Aufsatz
ISSN: 0009-2509
Secondary publication: yes
Document version: Postprint
DOI: 10.26092/elib/2459
URN: urn:nbn:de:gbv:46-elib71384
Institution: Universität Bremen 
Faculty: Zentrale Wissenschaftliche Einrichtungen und Kooperationen 
Institute: Zentrum für Umweltforschung und nachhaltige Technologien (UFT) 
Appears in Collections:Forschungsdokumente

  

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