Bifunctional submicron colloidosomes coassembled from fluorescent and superparamagnetic nanoparticles
Veröffentlichungsdatum
2015-01-02
Zusammenfassung
Colloidosomes are microcapsules consisting of nanoparticle shells. These microcarriers can be self-assembled from a wide range of colloidal particles with selective chemical, physical, and morphological properties and show promise for application in the field of theranostic nanomedicine. Previous studies have mainly focused on fairly large colloidosomes (>1 μm) based on a single kind of particle; however, the intrinsic building-block nature of this microcarrier has not been exploited so far for the introduction of tailored functionality at the nanoscale. We report a synthetic route based on interfacial shear rheology studies that allows the simultaneous incorporation of different nanoparticles with distinct physical properties, that is, superparamagnetic iron oxide and fluorescent silica nanoparticles, in a single submicron colloidosome. These tailor-made microcapsules can potentially be used in various biomedical applications, including magnetic hyperthermia, magnetic particle imaging, drug targeting, and bioimaging.
Schlagwörter
colloidosomes
;
fluorescence
;
interfacial shear rheology
;
superparamagnetism
;
theranostics
;
Mimenima
Verlag
Wiley-VCH Verlag GmbH & Co. KGaA, Weilheim
Institution
Fachbereich
Institute
Fachgebiet 17: Keramische Werkstoffe und Bauteile
Dokumenttyp
Artikel/Aufsatz
Zeitschrift/Sammelwerk
Startseite
118
Endseite
123
Zweitveröffentlichung
Ja
Dokumentversion
Postprint
Lizenz
Sprache
Englisch
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Name
Bifunctional Submicron Colloidosomes Coassembled from Fluorescent and Superparamagnetic Nanoparticles.pdf
Size
2.58 MB
Format
Adobe PDF
Checksum
(MD5):81f7151e22f7d6d075c210cb66122f77