Statistische Methoden zur Replizierbarkeitsbewertung im Rahmen mehrstufiger Studien
Veröffentlichungsdatum
2022-04-21
Autoren
Betreuer
Gutachter
Zusammenfassung
In replicability analyses, we are concerned with the analysis of partial conjunction null hypotheses. Valid combination p-values for the latter are often too large. Randomized p-values replace too large p-values with a random number between zero and one, whereas conditional p-values discard these entirely; both need to rescale the remaining p-values. In a multiple testing setup, where many partial conjunction null hypotheses are considered, using either can for example improve the estimation of the proportion of true null hypotheses or the power of a multiple test. Furthermore an analysis of different combination functions in different settings has been conducted, some turning out to be more advantageous for spread-out evidence and others for sparse evidence.
Schlagwörter
conditional p-values
;
false discovery rate
;
Fisher method
;
multiple testing
;
partial conjunction
;
proportion of true null hypotheses
;
randomized p-values
;
reversed hazard rate
;
Schweder-Spjotvoll estimator.
;
Stouffer method
Institution
Fachbereich
Dokumenttyp
Dissertation
Zweitveröffentlichung
Nein
Sprache
Englisch
Dateien![Vorschaubild]()
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Name
dissertation_hoang.pdf
Size
2.58 MB
Format
Adobe PDF
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