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  4. Control of Stereoselectivity in Heterogeneous Catalysis by Functionalization of Pt Nanoparticles with alpha-Amino Acids
 
Zitierlink URN
https://nbn-resolving.de/urn:nbn:de:gbv:46-00107467-16

Control of Stereoselectivity in Heterogeneous Catalysis by Functionalization of Pt Nanoparticles with alpha-Amino Acids

Veröffentlichungsdatum
2019-06-14
Autoren
Sulce, Anda  
Betreuer
Kunz, Sebastian  
Gutachter
Bäumer, Marcus  
Zusammenfassung
The asymmetric hydrogenation of ß-keto esters over amino acid-functionalized Pt nanoparticles (NPs) was explored. The investigated catalysts are chemoselective and stereoselective due to specific ligand-reactant interactions between ligands and reactants. Based on structure-selectivity relationships, the previously for L-proline-functionalized Pt NPs suggested ligand-reactant interaction model could be validated, extended to other amino acid ligands, and further refined. Nonlinear effect analysis revealed that in most cases the stereoselectivity is determined mainly by a 1:1 ligand-reactant interaction. Adjusting the interactions between ligands and reactants allowed to improve the stereoselectivity up to an enantiomeric excess over 80%. Most amino acid ligands not only induce selectivity but also enhance the reaction rate. The results of a systematic kinetic study provided an important contribution to the understanding of the reaction mechanism.
Schlagwörter
Ligand-functionalized nanoparticles

; 

ligand-reactant interactions

; 

nonlinear effects

; 

stereoselective heterogeneous catalysis

; 

asymmetric hydrogenation

; 

ligand acceleration effect

; 

reaction kinetics
Institution
Universität Bremen  
Fachbereich
Fachbereich 02: Biologie/Chemie (FB 02)  
Dokumenttyp
Dissertation
Zweitveröffentlichung
Nein
Sprache
Englisch
Dateien
Lade...
Vorschaubild
Name

00107467-1.pdf

Size

4.77 MB

Format

Adobe PDF

Checksum

(MD5):ad18bffc50ed4b7b5e12c3832cee346c

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