Gabel, DetlefHoffmann, SaschaSaschaHoffmann2020-03-092020-03-092006-09-26https://media.suub.uni-bremen.de/handle/elib/2277The DNA of cancer cells can be targeted by several synthetic DNA minor groove binding drugs. In combination with boron these DNA minor groove binding drugs can be the source of interesting compounds for possible use in BNCT (boron neutron capture therapy). In this work, we present several possible synthetic ways in the preparation of B12H11-containing derivatives and model compounds of the well known heterocyclic DNA minor groove binding drugs DB 75 and DB 293, by the use of using several known and new methods for the connection of B12H11-boron cluster derivatives to organic moeties.deinfo:eu-repo/semantics/openAccessDNAminor groove bindersBNCTB12H11-containing minor groove binders540Dissertationurn:nbn:de:gbv:46-diss000104672