Schrey, HeddaHeddaSchreyScheele, TarekTarekScheeleUlonska, ConradConradUlonskaNedder, Dana LeoniDana LeoniNedderNeudecker, TimTimNeudeckerSpiteller, PeterPeterSpitellerStadler, MarcMarcStadler2025-02-272025-02-272022-09-210163-3864https://media.suub.uni-bremen.de/handle/elib/8769https://doi.org/10.26092/elib/3678Seven sesquiterpenoids, named nebucanes A–G (1–7), featuring a rare alliacane scaffold with unprecedented furan or pyrrole functions, were isolated from the fermentation broth of Clitocybe nebularis. Their structures were established on the basis of 1D/2D NMR spectroscopic analyses, HR-(+)-ESIMS spectra, and comparison of measured and calculated CD spectra for determination of the absolute configuration. Assessing the biological activities, nebucane D (4) exhibited antifungal effects against Rhodotorula glutinis, while nebucane G (7) displayed significant cytotoxicity against MCF-7 and A431 cell lines.enAlle Rechte vorbehaltenAlle Rechte vorbehaltenAbsolute configurationCarbonChemical structureCircular dichroism spectroscopySesquiterpenoids540Text::Zeitschrift::Wissenschaftlicher Artikel10.26092/elib/3678urn:nbn:de:gbv:46-elib87695