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  4. Prognoseparameter bei soliden Tumoren und Systemerkrankungen
 
Zitierlink URN
https://nbn-resolving.de/urn:nbn:de:gbv:46-00101911-10

Prognoseparameter bei soliden Tumoren und Systemerkrankungen

Veröffentlichungsdatum
2010-07-06
Autoren
Meyer, Anke  
Betreuer
Bullerdiek, Jörn  
Gutachter
Mädler, Kathrin  
Zusammenfassung
Solid tumors and malignant systemic diseases are two of the most severe burdens of the world. The incidence rate of more than 11 million cases per year is considerably high. For this reason new methods and knowledge are required. By the methods developed and relations given in this dissertation a big step forward in cancer research is realized. New possibilities to measure gene expression of pseudogene rich gene families were established. Furthermore multifaceted gene expression profiles for prognostic parameters such as HMGA2, HMGB1, uPA, PAI1, Her2neu were established, analysed, and discussed. The presented work underlines the significantly high influence of HMG proteins in cancer development. New approaches and starting points for further analyses are identified and are the basis to upgrade diagnosis, prognosis, and therapy of cancer patients.
Schlagwörter
HMGA2

; 

HMGB1

; 

cancer

; 

prognosis
Institution
Universität Bremen  
Fachbereich
Fachbereich 02: Biologie/Chemie (FB 02)  
Dokumenttyp
Dissertation
Zweitveröffentlichung
Nein
Sprache
Deutsch
Dateien
Lade...
Vorschaubild
Name

00101911-1.pdf

Size

13.37 MB

Format

Adobe PDF

Checksum

(MD5):bdd43a5acd621539b10e1b0ce8428b5e

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