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Synthese von mehrfach geladenen closo-Dodecaborat-Derivaten und borhaltigen Lipiden
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Other Titles: | Synthesis of multiple charged closo-dodecaborate derivatives and boron-containing lipids | Authors: | Luyi, Wang | Supervisor: | Gabel, Detlef | 1. Expert: | Gabel, Detlef | 2. Expert: | Massing, Ulrich | Abstract: | The boron neutron capture therapy (BNCT) opens a fascinatingly perspective for cancer treatment. Non toxic or low toxic boron-containing compounds are used in BNCT. Therefore, the first part of the work is the synthesis of amphiphilic boron compounds. In particular, neutral and singly positively charged lipid-like compounds were synthesized. The second part of this work is the synthesis of a six negatively charged fluorescent boron compound. |
Keywords: | BNCT, boron containing lipid, closo-dodecaborate, fluorescence, zeta potential, dissociation constant, toxicity | Issue Date: | 4-Dec-2013 | Type: | Dissertation | URN: | urn:nbn:de:gbv:46-00103617-16 | Institution: | Universität Bremen | Faculty: | FB2 Biologie/Chemie |
Appears in Collections: | Dissertationen |
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