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Citation link: http://nbn-resolving.de/urn:nbn:de:gbv:46-00103617-16
00103617-1.pdf
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Synthese von mehrfach geladenen closo-Dodecaborat-Derivaten und borhaltigen Lipiden


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Other Titles: Synthesis of multiple charged closo-dodecaborate derivatives and boron-containing lipids
Authors: Luyi, Wang 
Supervisor: Gabel, Detlef
1. Expert: Gabel, Detlef
2. Expert: Massing, Ulrich 
Abstract: 
The boron neutron capture therapy (BNCT) opens a fascinatingly perspective for cancer treatment. Non toxic or low toxic boron-containing compounds are used in BNCT. Therefore, the first part of the work is the synthesis of amphiphilic boron compounds. In particular, neutral and singly positively charged lipid-like compounds were synthesized. The second part of this work is the synthesis of a six negatively charged fluorescent boron compound.
Keywords: BNCT, boron containing lipid, closo-dodecaborate, fluorescence, zeta potential, dissociation constant, toxicity
Issue Date: 4-Dec-2013
Type: Dissertation
URN: urn:nbn:de:gbv:46-00103617-16
Institution: Universität Bremen 
Faculty: FB2 Biologie/Chemie 
Appears in Collections:Dissertationen

  

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