Synthese von mehrfach geladenen closo-Dodecaborat-Derivaten und borhaltigen Lipiden
|Other Titles:||Synthesis of multiple charged closo-dodecaborate derivatives and boron-containing lipids||Authors:||Luyi, Wang||Supervisor:||Gabel, Detlef||1. Expert:||Gabel, Detlef||2. Expert:||Massing, Ulrich||Abstract:||
The boron neutron capture therapy (BNCT) opens a fascinatingly perspective for cancer treatment. Non toxic or low toxic boron-containing compounds are used in BNCT. Therefore, the first part of the work is the synthesis of amphiphilic boron compounds. In particular, neutral and singly positively charged lipid-like compounds were synthesized. The second part of this work is the synthesis of a six negatively charged fluorescent boron compound.
|Keywords:||BNCT, boron containing lipid, closo-dodecaborate, fluorescence, zeta potential, dissociation constant, toxicity||Issue Date:||4-Dec-2013||URN:||urn:nbn:de:gbv:46-00103617-16||Institution:||Universität Bremen||Faculty:||FB2 Biologie/Chemie|
|Appears in Collections:||Dissertationen|
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